Product Name: Zap-70 (L1E5) Mouse mAb#2709
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1221485-83-1
Product: Skepinone-L
Specificity Sensitivity: Zap-70 (L1E5) Mouse mAb detects endogenous levels of total Zap-70 protein. It does not cross-react with other related proteins.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding the Ser289 of human Zap-70.
Background: The Syk family protein tyrosine kinase Zap-70 is expressed in T and NK cells and plays a critical role in mediating T cell activation in response to T cell receptor (TCR) engagement (1). Following TCR engagement, Zap-70 is rapidly phosphorylated on severa
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19431184?dopt=Abstract
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