Product Name :
Diketone-PEG4-PFP ester
Description:
Diketone-PEG4-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
2353409-84-2
Molecular Weight:
647.58
Formula:
C30H34F5NO9
Chemical Name:
2,3,4,5,6-pentafluorophenyl 1-{[4-(3,5-dioxohexyl)phenyl]carbamoyl}-3,6,9,12-tetraoxapentadecan-15-oate
Smiles :
CC(=O)CC(=O)CCC1C=CC(=CC=1)NC(=O)CCOCCOCCOCCOCCC(=O)OC1C(F)=C(F)C(F)=C(F)C=1F
InChiKey:
YJNZZHGXYBSDRO-UHFFFAOYSA-N
InChi :
InChI=1S/C30H34F5NO9/c1-19(37)18-22(38)7-4-20-2-5-21(6-3-20)36-23(39)8-10-41-12-14-43-16-17-44-15-13-42-11-9-24(40)45-30-28(34)26(32)25(31)27(33)29(30)35/h2-3,5-6H,4,7-18H2,1H3,(H,36,39)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Diketone-PEG4-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|CAS Number: 2353409-84-2|Molecular Weight: 647.58|Formula: C30H34F5NO9|Chemical Name: 2,3,4,5,6-pentafluorophenyl 1-{[4-(3,5-dioxohexyl)phenyl]carbamoyl}-3,6,9,12-tetraoxapentadecan-15-oate|Smiles: CC(=O)CC(=O)CCC1C=CC(=CC=1)NC(=O)CCOCCOCCOCCOCCC(=O)OC1C(F)=C(F)C(F)=C(F)C=1F|InChiKey: YJNZZHGXYBSDRO-UHFFFAOYSA-N|InChi: InChI=1S/C30H34F5NO9/c1-19(37)18-22(38)7-4-20-2-5-21(6-3-20)36-23(39)8-10-41-12-14-43-16-17-44-15-13-42-11-9-24(40)45-30-28(34)26(32)25(31)27(33)29(30)35/h2-3,5-6H,4,7-18H2,1H3,(H,36,39)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{GMP EGF Protein, Human} site|{GMP EGF Protein, Human} Biological Activity|{GMP EGF Protein, Human} In Vitro|{GMP EGF Protein, Human} custom synthesis|{GMP EGF Protein, Human} Cancer} |Shelf Life: ≥12 months if stored properly.{{Loxapine} site|{Loxapine} Dopamine Receptor|{Loxapine} Purity & Documentation|{Loxapine} In Vivo|{Loxapine} custom synthesis|{Loxapine} Epigenetics} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:31686535 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|
