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Product Name :
TJ191

Description:
TJ191 is a potent and specific anti-cancer agent that targets low TβRIII-expressing malignant T-cell leukemia/lymphoma cells. TJ191 has no affects on the proliferation of other cancer cells or normal fibroblasts or immune cells. TJ191 can be used for cancer research.

CAS:
1522415-97-9

Molecular Weight:
255.38

Formula:
C13H21NO2S

Chemical Name:
methyl 2-amino-5-heptylthiophene-3-carboxylate

Smiles :
CCCCCCCC1=CC(=C(N)S1)C(=O)OC

InChiKey:
HUFNXSPJUAHQHP-UHFFFAOYSA-N

InChi :
InChI=1S/C13H21NO2S/c1-3-4-5-6-7-8-10-9-11(12(14)17-10)13(15)16-2/h9H,3-8,14H2,1-2H3

Purity:
≥98% (or refer to the Certificate of Analysis)

Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life:
≥12 months if stored properly.{{Thiamine} web|{Thiamine} Anti-infection|{Thiamine} Purity & Documentation|{Thiamine} In stock|{Thiamine} supplier|{Thiamine} Autophagy}

Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.

Additional information:
TJ191 is a potent and specific anti-cancer agent that targets low TβRIII-expressing malignant T-cell leukemia/lymphoma cells. TJ191 has no affects on the proliferation of other cancer cells or normal fibroblasts or immune cells. TJ191 can be used for cancer research.|Product information|CAS Number: 1522415-97-9|Molecular Weight: 255.38|Formula: C13H21NO2S|Chemical Name: methyl 2-amino-5-heptylthiophene-3-carboxylate|Smiles: CCCCCCCC1=CC(=C(N)S1)C(=O)OC|InChiKey: HUFNXSPJUAHQHP-UHFFFAOYSA-N|InChi: InChI=1S/C13H21NO2S/c1-3-4-5-6-7-8-10-9-11(12(14)17-10)13(15)16-2/h9H,3-8,14H2,1-2H3|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Mecillinam} MedChemExpress|{Mecillinam} Antibiotic|{Mecillinam} Epigenetics|{Mecillinam} Protocol|{Mecillinam} In Vitro|{Mecillinam} supplier} |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|TJ191(0-100 µM; 24 hours) exhibits pronounced anti-proliferative activity in malignant cell lines, the IC50 values are 0.PMID:24101108 13 µM, 0.13±0.08 µM, 0.26±0.19 µM, 0.22±0.11 µM, 1.5±0.02 µM, 0.32±0.086 µM, 3.1±0.5 µM, 0.26±0.16 µM in CEM, JURKAT, MOLT-3, MOLT-4, SUP-T1, MT-2, C8166 and HSB-2 cells, respectively. But has no effects in HUT-78 (IC50=17±10 µM) and MT-4 (IC50=47 ± 5 µM) cells. TJ191 (0.1-3 µM; 8 or 24 hours) induces CEM cell apoptosis in a concentration- and time-dependent manner. Even at 0.3 µM, TJ191 induces the maximum apoptotic rate of 80% after 24 h.|Products are for research use only. Not for human use.|

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Author: Interleukin Related