Product Name :
AWL-II-38.3
Description:
AWL-II-38.3 is a potent ephrin-A receptor (EphA3) kinase inhibitor. AWL-II-38.3 does not exhibit significant cellular activity against Src-family kinases nor against b-raf.
CAS:
1135205-94-5
Molecular Weight:
469.42
Formula:
C23H18F3N5O3
Chemical Name:
N-{2-methyl-5-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzamido]phenyl}-1,2-oxazole-5-carboxamide
Smiles :
CC1=CC=C(C=C1NC(=O)C1=CC=NO1)NC(=O)C1C=C(C=C(C=1)N1C=NC(C)=C1)C(F)(F)F
InChiKey:
IYUFHBXMTTXZBE-UHFFFAOYSA-N
InChi :
InChI=1S/C23H18F3N5O3/c1-13-3-4-17(10-19(13)30-22(33)20-5-6-28-34-20)29-21(32)15-7-16(23(24,25)26)9-18(8-15)31-11-14(2)27-12-31/h3-12H,1-2H3,(H,29,32)(H,30,33)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
AWL-II-38.3 is a potent ephrin-A receptor (EphA3) kinase inhibitor. AWL-II-38.3 does not exhibit significant cellular activity against Src-family kinases nor against b-raf.|Product information|CAS Number: 1135205-94-5|Molecular Weight: 469.42|Formula: C23H18F3N5O3|Chemical Name: N-{2-methyl-5-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzamido]phenyl}-1,2-oxazole-5-carboxamide|Smiles: CC1=CC=C(C=C1NC(=O)C1=CC=NO1)NC(=O)C1C=C(C=C(C=1)N1C=NC(C)=C1)C(F)(F)F|InChiKey: IYUFHBXMTTXZBE-UHFFFAOYSA-N|InChi: InChI=1S/C23H18F3N5O3/c1-13-3-4-17(10-19(13)30-22(33)20-5-6-28-34-20)29-21(32)15-7-16(23(24,25)26)9-18(8-15)31-11-14(2)27-12-31/h3-12H,1-2H3,(H,29,32)(H,30,33)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Firibastat} MedChemExpress|{Firibastat} Aminopeptidase|{Firibastat} Biological Activity|{Firibastat} Purity|{Firibastat} manufacturer|{Firibastat} Epigenetic Reader Domain} |Shelf Life: ≥12 months if stored properly.{{Chrysene-d12} web|{Chrysene-d12} {Isotope-Labeled Compounds}|{Chrysene-d12} Technical Information|{Chrysene-d12} In Vivo|{Chrysene-d12} custom synthesis|{Chrysene-d12} Epigenetics} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:32776252 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|AWL-II-38.3 fits to LIMK2 and LIMK1 ATP-binding and substrate-binding pockets.|Products are for research use only. Not for human use.|
