Product Name: TopBP1 (D8G4L) Rabbit mAb#14342
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:100
Immunohistochemistry:
Peptide ELISA:
Storage:
CAS NO.: 899431-18-6
Product: A 438079 (hydrochloride)
Specificity Sensitivity: TopBP1 (D8G4L) Rabbit mAb recognizes endogenous levels of total TopBP1 protein.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Leu27 of human TopBP1 protein.
Background: Topoisomerase II Binding Protein 1 (TopBP1) contains eight BRCT domains, which facilitate interaction with various proteins, phosphopeptides, and DNA. Through these interactions, TopBP1 functions in the regulation of DNA replication, DNA repair, checkpoin
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/17050671?dopt=Abstract
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