Product Name: Phospho-Topoisomerase IIα (Ser1469) (D4F5) Rabbit mAb#13072
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 43229-80-7
Product: Formoterol (Fumarate)
Specificity Sensitivity: Phospho-Topoisomerase IIα (Ser1469) (D4F5) Rabbit mAb recognizes endogenous levels of topoisomerase IIα protein only when phosphorylated at Ser1469.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ser1469 of human topoisomerase IIα protein.
Background: DNA topoisomerases I and II are nuclear enzymes; type II consists of two highly homologous isoforms: topoisomerase IIα and IIβ. These enzymes regulate the topology of DNA, maintain genomic integrity, and are essential for processes such as DNA replication
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/16822840?dopt=Abstract
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