Product Name: Phospho-TBC1D1 (Ser660) Antibody#6928
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 487021-52-3
Product: AR-A014418
Specificity Sensitivity: Phospho-TBC1D1 (Ser660) Antibody recognizes transfected levels of TBC1D1 protein only when phosphorylated at Ser660.
Species Reactivity: Mouse
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ser660 of mouse TBC1D1 protein. Antibodies are purified by protein A and peptide affinity chromatography.
Background: TBC1D1 is a paralog of AS160 (1) and both proteins share about 50% identity (2). TBC1D1 was shown to be a candidate gene for severe obesity (3). It plays a role in Glut4 translocation through its GAP activity (2,4). Studies indicate that TBC1D1 is highly
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20053638?dopt=Abstract
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