Product Name: Phospho-α-Synuclein (Ser129) (D1R1R) Rabbit mAb#23706
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 500579-04-4
Product: GANT 61
Specificity Sensitivity: Phospho-α-Synuclein (Ser129) (D1R1R) Rabbit mAb recognizes endogenous levels of α-Synuclein protein only when phosphorylated at Ser129. Specificity of nuclear staining is unclear but consistent with previous publications (4).
Species Reactivity: Human, Mouse, Rat
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ser129 of human α-Synuclein protein.
Background: α-Synuclein is a protein of 140-amino acids expressed abundantly in the brain. α-Synuclein is also the main component of pathogenic Lewy bodies and Lewy neurites. Research studies have shown that mutations of the α-synuclein gene are linked to Parkinsons
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23963803?dopt=Abstract
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