Product Name: SQSTM1/p62 (D10E10) Rabbit mAb (IF Preferred)#7695
Application: Dilutions
Western Blotting:
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 661464-94-4
Product: Levalbuterol (tartrate)
Specificity Sensitivity: SQSTM1/p62 (D10E10) Rabbit mAb (IF Preferred) is recommended to detect endogenous levels of total SQSTM1/p62 protein by immunofluorescence. Products SQSTM1/p62 (D5E2) Rabbit mAb #8025 and SQSTM1/p62 Antibody #5114 are preferred for western blot.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human SQSTM1/p62 protein.
Background: Sequestosome 1 (SQSTM1, p62) is a ubiquitin binding protein involved in cell signaling, oxidative stress, and autophagy (1-4). It was first identified as a protein that binds to the SH2 domain of p56Lck (5) and independently found to interact with PKCζ (6
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23950950?dopt=Abstract
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