Product Name: SQSTM1/p62 (D5E2) Rabbit mAb#8025
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:100
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1345675-02-6
Product: ETP-46464
Specificity Sensitivity: SQSTM1/p62 (D5E2) Rabbit mAb recognizes endogenous levels of total SQSTM1/p62 protein.
Species Reactivity: Human, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Gly162 of human SQSTM1/p62 protein.
Background: Sequestosome 1 (SQSTM1, p62) is a ubiquitin binding protein involved in cell signaling, oxidative stress, and autophagy (1-4). It was first identified as a protein that binds to the SH2 domain of p56Lck (5) and independently found to interact with PKCζ (6
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25206282?dopt=Abstract
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