Product Name: α/β-Synuclein (Syn205) Mouse mAb#2644
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry: 1:100
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 41276-02-2
Product: TIC10 isomer
Specificity Sensitivity: α/β-Synuclein (Syn205) Mouse mAb detects endogenous levels of total synuclein protein. α/β-Synuclein (Syn205) Mouse mAb detects recombinant α and β-synuclein (Giasson, B.I. et al., 2000).
Species Reactivity: Human, Mouse, Rat
Source Purification: Monoclonal antibody is produced by immunizing animals with human recombinant α- and β-synucleins and the epitope maps to the carboxy terminus of the protein.
Background: α-Synuclein is a protein of 140-amino acids expressed abundantly in the brain. α-Synuclein is also the main component of pathogenic Lewy bodies and Lewy neurites. Research studies have shown that mutations of the α-synuclein gene are linked to Parkinsons
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23382546?dopt=Abstract
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