Product Name: Snail (SN9H2) Rat mAb#4719
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1191252-49-9
Product: IOWH-032
Specificity Sensitivity: Snail (SN9H2) Rat mAb detects endogenous levels of total Snail.
Species Reactivity: Human, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with a recombinant human Snail protein.
Background: Snail is a zinc-finger transcription factor that can repress E-cadherin transcription. Downregulation of E-cadherin is associated with epithelial-mesenchymal transition during embryonic development, a process also exploited by invasive cancer cells (1-3).
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/15347678?dopt=Abstract
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