Product Name: Snail (C15D3) Rabbit mAb#3879
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 56995-20-1
Product: Flupirtine
Specificity Sensitivity: Snail (C15D3) Rabbit mAb detects endogenous levels of total Snail protein.
Species Reactivity: Human, Mouse, Rat, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with a recombinant human Snail protein.
Background: Snail is a zinc-finger transcription factor that can repress E-cadherin transcription. Downregulation of E-cadherin is associated with epithelial-mesenchymal transition during embryonic development, a process also exploited by invasive cancer cells (1-3).
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/18060687?dopt=Abstract
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