Product Name: Phospho-Shc (Tyr317) Antibody#2431
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 151096-09-2
Product: Moxifloxacin
Specificity Sensitivity: Phospho-Shc (Tyr317) Antibody detects Shc only when phosphorylated at Tyr317.
Species Reactivity: Human, Mouse
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr317 of human Shc. Antibodies are purified by protein A and peptide affinity chromatography.
Background: Shc possesses SH2 and PTB domains and serves as a scaffold protein in signaling for a variety of receptor tyrosine kinases. Shc exists in p46, p52 and p66 isoforms, which are produced by using alternative translation initiation sites or a differentially s
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19730740?dopt=Abstract
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