Product Name: Phospho-SAPK/JNK (Thr183/Tyr185) (81E11) Rabbit mAb#4668
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:200
Immunohistochemistry: 1:100
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 69-72-7
Product: Salicylic acid
Specificity Sensitivity: Phospho-SAPK/JNK (Thr183/Tyr185) (81E11) Rabbit mAb detects endogenous levels of p46 and p54 SAPK/JNK only when phosphorylated at Thr183 and Tyr185. This antibody may cross-react with phosphorylated p44/42 or p38 MAP kinases.
Species Reactivity: Human, Mouse, Rat, D. melanogaster, S. cerevisiae
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Thr183/Tyr185 of human SAPK/JNK.
Background: The stress-activated protein kinase/Jun-amino-terminal kinase SAPK/JNK is potently and preferentially activated by a variety of environmental stresses including UV and gamma radiation, ceramides, inflammatory cytokines, and in some instances, growth facto
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23576437?dopt=Abstract
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