Product Name: S6 Ribosomal Protein (5G10) Rabbit mAb#2217
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry: 1:100
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1421373-66-1
Product: AZD-9291 (mesylate)
Specificity Sensitivity: S6 Ribosomal Protein (5G10) Rabbit Monoclonal Antibody detects endogenous levels of total S6 ribosomal protein independent of phosphorylation.
Species Reactivity: Human, Mouse, Rat, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues of human S6 ribosomal protein.
Background: One way that growth factors and mitogens effectively promote sustained cell growth and proliferation is by upregulating mRNA translation (1,2). Growth factors and mitogens induce the activation of p70 S6 kinase and the subsequent phosphorylation of the S6
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25153886?dopt=Abstract
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