Product Name: RBX1 Antibody#4397
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 63547-13-7
Product: Adrafinil
Specificity Sensitivity: RBX1 Antibody detects endogenous levels of total RBX1 protein.
Species Reactivity: Human, Mouse, Rat, Monkey
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the amino terminus of human RBX1 protein. Antibodies were purified by protein A and peptide affinity chromatography.
Background: RING-box protein 1 (RBX1 or ROC1) is an essential component of two distinct but structurally related E3 ubiquitin ligase complexes, the SCF complex and the CBC (VHL) complex (1). RBX1 mediates the neddylation of CUL1, which activates SCF E3 ligase by faci
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24717432?dopt=Abstract
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