Product Name: EPAC2 (D3P3J) Rabbit mAb#43239
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:100
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 50-23-7
Product: Hydrocortisone
Specificity Sensitivity: EPAC2 (D3P3J) Rabbit mAb recognizes endogenous levels of total EPAC2 protein.
Species Reactivity: Human, Mouse, Rat
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Gln975 of human EPAC2 protein.
Background: EPAC1 and EPAC2 (exchange proteins activated by cyclic AMP) are guanine nucleotide exchange factors (GEFs) that catalyze the exchange of GDP for GTP, activating Rap1 and Rap2 small GTPases. Rap activation by EPAC is cAMP-dependent and mediates cAMP signal
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19680541?dopt=Abstract
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