Product Name: A-Raf Antibody#4432
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 129618-40-2
Product: Nevirapine
Specificity Sensitivity: A-Raf Antibody detects endogenous levels of total A-Raf. This antibody does not cross-react with c-Raf or B-Raf.
Species Reactivity: Human, Mouse, Rat
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues close to the linker domain of human A-Raf. Antibodies are purified by protein A and peptide affinity chromatography.
Background: A-Raf, B-Raf, and c-Raf (Raf-1) are the main effectors recruited by GTP-bound Ras to activate the MEK-MAP kinase pathway (1). Activation of c-Raf is the best understood and involves phosphorylation at multiple activating sites including Ser338, Tyr341, Th
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25536043?dopt=Abstract
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