Product Name: Phospho-Rad50 (Ser635) Antibody#14223
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 7235-40-7
Product: β-Carotene
Specificity Sensitivity: Phospho-Rad50 (Ser635) Antibody recognizes endogenous levels of Rad50 protein only when phosphorylated at Ser635.
Species Reactivity: Human
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser635 of human Rad50 protein. Antibodies are purified by protein A and peptide affinity chromatography.
Background: The DNA repair protein Rad50 is a member of the structural maintenance of chromosomes family (SMC) and plays an important role in cell cycle checkpoint signaling and double-strand break repair in response to DNA damage (1-4). Rad50 forms a complex with Mr
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20690663?dopt=Abstract
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