Product Name: PZR Antibody#4157
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 64872-77-1
Product: Butoconazole (nitrate)
Specificity Sensitivity: PZR Antibody detects endogenous levels of total PZR protein.
Species Reactivity: Human, Monkey
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the N terminus of human PZR. Antibodies are purified by protein A and peptide affinity chromatography.
Background: PZR (Protein zero related) is an immunoglobulin superfamily protein that specifically binds the tyrosine phosphatase SHP-2 through its intracellular immunoreceptor tyrosine-based inhibitory motifs (ITIMs) (1,2). PZR is phosphorylated by c-Src, c-Fyn, c-Ly
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20932480?dopt=Abstract
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