Product Name: PREX1 (D8O8D) Rabbit mAb#13168
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 92077-78-6
Product: Cilazapril (monohydrate)
Specificity Sensitivity: PREX1 (D8O8D) Rabbit mAb recognizes endogenous levels of total PREX1 protein. This antibody will recognize both isoform 1 (190 kDa) and isoform 2 (110 kDa) human PREX1, but has not been observed to cross-react with human PREX2 protein.
Species Reactivity: Human, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding His770 of human PREX1 protein.
Background: Phosphoinositide-3,4,5-triphosphate (PtdIns(3,4,5)P3)-dependent Rac exchanger 1 (PREX1) is a Rac-specific GTP-exchange factor (GEF) regulated by heterotrimeric G-protein β/γ subunits and the lipid second messenger PtdIns(3,4,5)P3 (1-4). PREX1 contains two
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24672033?dopt=Abstract
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