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Product Name: Prdx1 (D5G12) Rabbit mAb#8499
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 56974-61-9
Product: Gabexate (mesylate)
Specificity Sensitivity: Prdx1 (D5G12) Rabbit mAb recognizes endogenous levels of total Prdx1 protein. This antibody does not cross-react with Prdx2 protein.
Species Reactivity: Human, Mouse, Rat, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Arg110 of human Prdx1 protein.
Background: Prdx1 belongs to a family of non-seleno peroxidases that function as H2O2 scavengers. All 6 Prdx isoforms share a conserved N-terminal cysteine (Cys51) that is oxidized by H2O2 to form cysteine-sulfenic acid (Cys51-SOH) and, in turn, reacts with Cys172-SH
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20081107?dopt=Abstract

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Author: Interleukin Related