Product Name: Phospho-Prdx1 (Tyr194) (D1T9C) Rabbit mAb#14041
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 161735-79-1
Product: Rasagiline (mesylate)
Specificity Sensitivity: Phospho-Prdx1 (Tyr194) (D1T9C) Rabbit mAb recognizes endogenous levels of Prdx1 protein only when phosphorylated at Tyr194. This antibody may cross react with other activated receptor tyrosine kinases including EGFR.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr194 of human Prdx1 protein.
Background: Prdx1 belongs to a family of non-seleno peroxidases that function as H2O2 scavengers. All 6 Prdx isoforms share a conserved N-terminal cysteine (Cys51) that is oxidized by H2O2 to form cysteine-sulfenic acid (Cys51-SOH) and, in turn, reacts with Cys172-SH
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20214829?dopt=Abstract
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