Product Name: EPAC1 (5D3) Mouse mAb#4155
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 51940-44-4
Product: Pipemidic acid
Specificity Sensitivity: Epac1 (5D3) Mouse mAb detects endogenous levels of total Epac1 protein.
Species Reactivity: Human, Mouse, Rat
Source Purification: Monoclonal antibody is produced by immunizing animals with a recombinant fragment of human Epac1.
Background: EPAC1 and EPAC2 (exchange proteins activated by cyclic AMP) are guanine nucleotide exchange factors (GEFs) that catalyze the exchange of GDP for GTP, activating Rap1 and Rap2 small GTPases. Rap activation by EPAC is cAMP-dependent and mediates cAMP signal
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23747949?dopt=Abstract
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