Product Name: Phospho-eIF4G (Ser1108) Antibody#2441
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:100
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 92478-27-8
Product: Morinidazole
Specificity Sensitivity: Phospho-eIF4G (Ser1108) Antibody detects eIF4GI only when phosphorylated at Ser1108. It does not cross-react with nonphosphorylated eIF4GI or p97.
Species Reactivity: Human, Mouse, Rat, Hamster, Monkey, Bovine
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Ser1108 of human eIF4GI. Antibodies are purified by protein A and peptide affinity chromatography.
Background: Eukaryotic initiation factor 4E (eIF4E) binds to the mRNA cap structure to mediate the initiation of translation (1,2). eIF4E interacts with eIF4G, a scaffold protein that promotes assembly of eIF4E and eIF4A into the eIF4F complex (2). eIF4B is thought t
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/26077467?dopt=Abstract
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