Product Name: EGF Receptor vIII (D6T2Q) XP® Rabbit mAb#64952
Application: Dilutions
Western Blotting:
Immunoprecipitation:
Immunohistochemistry: 1:200
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 64232-83-3
Product: L189
Specificity Sensitivity: EGF Receptor vIII (D6T2Q) XP® Rabbit mAb recognizes endogenous and transfected levels of EGF Receptor vIII protein by immunohistochemistry and immunofluorescence, respectively.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the amino terminus of human EGF Receptor vIII protein.
Background: The epidermal growth factor (EGF) receptor is a transmembrane tyrosine kinase that belongs to the HER/ErbB protein family. Ligand binding results in receptor dimerization, autophosphorylation, activation of downstream signaling, internalization, and lysos
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19997197?dopt=Abstract
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