Product Name: Phospho-EGF Receptor (Thr669) (D2F1) Rabbit mAb#8808
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:200
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 碌g/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at 鈥?0掳C. Do not aliquot the antibody.
CAS NO.: 57-88-5
Product: Cholesterol
Specificity Sensitivity: Phospho-EGF Receptor (Thr669) (D2F1) Rabbit mAb detects endogenous levels of EGFR protein only when phosphorylated at Thr669. While the literature refers to this residue as Thr669, it is Thr693 of human EGFR (UniProt sequence P00533) and corresponds to Th
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Thr693 of human EGFR protein.
Background: The epidermal growth factor (EGF) receptor is a transmembrane tyrosine kinase that belongs to the HER/ErbB protein family. Ligand binding results in receptor dimerization, autophosphorylation, activation of downstream signaling, internalization, and lysos
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20637071?dopt=Abstract
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