Product Name: Phospho-EGF Receptor (Tyr1173) (53A5) Rabbit mAb#4407
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry: 1:250
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 548-66-3
Product: Drofenine (hydrochloride)
Specificity Sensitivity: Phospho-EGF Receptor (Tyr1173) (53A5) Rabbit mAb detects endogenous EGF receptors only when phosphorylated at Tyr1173. This antibody may cross-react with other activated receptor tyrosine kinases.
Species Reactivity: Human, Mouse, Rat
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Tyr1173 of human EGF receptor.
Background: The epidermal growth factor (EGF) receptor is a transmembrane tyrosine kinase that belongs to the HER/ErbB protein family. Ligand binding results in receptor dimerization, autophosphorylation, activation of downstream signaling, internalization, and lysos
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23963759?dopt=Abstract
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