Product Name: Phospho-EGF Receptor (Thr678) Antibody#14343
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:100
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1825942
Product: DL-Glutamine
Specificity Sensitivity: Phospho-EGF Receptor (Thr678) Antibody recognizes endogenous levels of EGFR protein only when phosphorylated at Thr678.
Species Reactivity: Human
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic phospho-peptide corresponding to residues surrounding Thr678 of human EGFR protein. Antibodies are purified by protein A and peptide affinity chromatography.
Background: The epidermal growth factor (EGF) receptor is a transmembrane tyrosine kinase that belongs to the HER/ErbB protein family. Ligand binding results in receptor dimerization, autophosphorylation, activation of downstream signaling, internalization, and lysos
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24688819?dopt=Abstract
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