Product Name: Drosha (D30F3) Rabbit mAb#3410
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 152918-18-8
Product: IB-MECA
Specificity Sensitivity: Drosha (D30F3) Rabbit mAb detects endogenous levels of total Drosha protein.
Species Reactivity: Human, Mouse
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding His549 of human Drosha.
Background: Drosha was identified as a nuclear RNase III that catalyzes the initial step of microRNA (miRNA) processing (1). This enzyme processes the long primary transcript pri-miRNAs into stem-looped pre-miRNAs. Interference of Drosha results in the increase of pr
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/26045982?dopt=Abstract
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