Product Name: DR5 (D4E9) XP® Rabbit mAb#8074
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:100
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1351635-67-0
Product: ONO-4059 (analog)
Specificity Sensitivity: DR5 (D4E9) XP® Rabbit mAb recognizes endogenous levels of total DR5 protein. This antibody detects both the short and long isoforms of DR5.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Arg260 within the cytoplasmic region of human DR5 protein.
Background: The tumor necrosis factor receptor family, which includes TNF-RI, Fas, DR3, DR4, DR5, and DR6, plays an important role in the regulation of apoptosis in various physiological systems (1,2). The receptors are activated by a family of cytokines that include
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27490929?dopt=Abstract
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