Product Name: DR4 (D9S1R) Rabbit mAb#42533
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:100
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 198978-94-8
Product: 5(6)-ROX
Specificity Sensitivity: DR4 (D9S1R) Rabbit mAb recognizes endogenous levels of total DR4 protein.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with recombinant protein specific to the carboxy terminal, cytoplasmic domain of human DR4 protein.
Background: The tumor necrosis factor receptor family, which includes TNF-RI, Fas, DR3, DR4, DR5, and DR6, plays an important role in the regulation of apoptosis in various physiological systems (1,2). The receptors are activated by a family of cytokines that include
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19433268?dopt=Abstract
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