Product Name: DR3 (D4O3X) Rabbit mAb#20772
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 194785-18-7
Product: 6-ROX
Specificity Sensitivity: DR3 (D4O3X) Rabbit mAb recognizes endogenous levels of total DR3 protein. A band of unknown origin is detected at at 110 kDa in some cell lines.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Leu335 of human DR3 protein. The antigen resides within the cytoplasmic domain of DR3.
Background: The tumor necrosis factor receptor family, which includes TNF-RI, Fas, DR3, DR4, DR5, and DR6, plays an important role in the regulation of apoptosis in various physiological systems (1,2). The receptors are activated by a family of cytokines that include
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21364627?dopt=Abstract
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