Product Name: DOCK180 (C4C12) Rabbit mAb#4846
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:100
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 260430-02-2
Product: CY2
Specificity Sensitivity: DOCK180 (C4C12) Rabbit mAb recognizes endogenous levels of total DOCK180 protein.
Species Reactivity: Human, Mouse, Rat
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to the carboxy-terminal sequence of human DOCK180.
Background: DOCK180 and its partner, ELMO1, interact directly with one another to form an atypical two-part guanine nucleotide exchange factor (GEF) for the small GTPase Rac (1). Rac activation occurs in association with p130 Cas and Crk, which form a complex with DO
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24173687?dopt=Abstract
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