Product Name: DKK1 Antibody#4687
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 606-68-8
Product: NADH (disodium salt)
Specificity Sensitivity: DKK1 Antibody detects transfected levels of DKK1 protein. This antibody does not cross-react with DKK2.
Species Reactivity: Human
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Gln75 of human DKK1. Antibodies are purified by peptide affinity chromatography.
Background: Dickkopf (DKK) family proteins consist of four members DKK1, DKK2, DKK3 and DKK4 that function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5 and LRP6 (1,2). DKKs contain two cysteine-rich domains in which the positions of 10 cysteine resi
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/18256671?dopt=Abstract
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