Product Name: DKK1 (D5V6L) Rabbit mAb#48367
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:100
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1309684-94-3
Product: RO8994
Specificity Sensitivity: DKK1 (D5V6L) Rabbit mAb recognizes endogenous levels of total DKK1 protein.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the amino terminus of human DKK1 protein.
Background: Dickkopf (DKK) family proteins consist of four members DKK1, DKK2, DKK3 and DKK4 that function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5 and LRP6 (1,2). DKKs contain two cysteine-rich domains in which the positions of 10 cysteine resi
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19473725?dopt=Abstract
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