Product Name: Dicer (D38E7) Rabbit mAb#5362
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 110044-82-1
Product: MG-101
Specificity Sensitivity: Dicer (D38E7) Rabbit mAb detects endogenous levels of total Dicer protein.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ala1133 of human Dicer.
Background: Dicer is a member of the RNase III family that specifically cleaves double-stranded RNAs to generate microRNAs (miRNAs) (1). After long primary transcript pri-miRNAs are processed to stem-looped pre-miRNAs by Drosha (2), pre-miRNAs are transported to the
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19931229?dopt=Abstract
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