Product Name: DEPTOR/DEPDC6 (D9F5) Rabbit mAb#11816
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry: 1:1000
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 56-25-7
Product: Cantharidin
Specificity Sensitivity: DEPTOR/DEPDC6 (D9F5) Rabbit mAb recognizes endogenous levels of total DEPTOR/DEPDC6 protein.
Species Reactivity: Human, Rat, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Leu113 of human DEPTOR/DEPDC6 protein.
Background: DEPTOR/DEPDC6 is a component of both mTORC1 and mTORC2 complexes (1). It interacts with mTOR and inhibits mTORC1 and mTORC2 kinase activities (1). mTOR, along with casein kinase I, phosphorylates DEPTOR/DEPDC6 in the presence of growth signals, which lead
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27619626?dopt=Abstract
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