Product Name: Phospho-CD19 (Tyr531) Antibody#3571
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:100
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1313881-70-7
Product: ARQ-092
Specificity Sensitivity: Phospho-CD19 (Tyr531) Antibody detects endogenous levels of CD19 only when phosphorylated at tyrosine 531.
Species Reactivity: Human
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic phosphopeptide corresponding to residues around Tyr531 of human CD19. Antibodies are purified by protein A and peptide affinity chromatography.
Background: CD19 is a 95 kDa coreceptor, which amplifies the signaling cascade in B cells (1). On the B cell surface, CD19 associates with CD21, CD81 and Leu-13 to exert its function. The cytoplasmic tail of CD19 has nine conserved tyrosine residues playing critical
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/17981115?dopt=Abstract
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