Product Name: Bcl-2 Antibody (Human Specific)#2872
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 344897-95-6
Product: Leukadherin-1
Specificity Sensitivity: Bcl-2 antibody (Human Specific) detects endogenous levels of total Bcl-2 protein. The antibody does not cross-react with other Bcl-2 family members.
Species Reactivity: Human
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Gly41 of human Bcl-2, a region not conserved in mouse or rat. Antibodies are purified by protein A and peptide affinity chromatography.
Background: Bcl-2 exerts a survival function in response to a wide range of apoptotic stimuli through inhibition of mitochondrial cytochrome c release (1). It has been implicated in modulating mitochondrial calcium homeostasis and proton flux (2). Several phosphoryla
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/26424893?dopt=Abstract
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