Product Name: β-Amyloid (pE3 Peptide) (D5N5H) Rabbit mAb#14975
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry: 1:100
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 342639-96-7
Product: KRIBB11
Specificity Sensitivity: β-Amyloid (pE3 Peptide) (D5N5H) Rabbit mAb recognizes recombinant pE3 form of β-amyloid peptides. This antibody does not cross-react with the non-pyroglutamate (E3) form of β-amyloid peptides.
Species Reactivity: Human
Source Purification: Monoclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues near the amino terminus of β-amyloid (pE3) peptide.
Background: Amyloid β (Aβ) precursor protein (APP) is a 100-140 kDa transmembrane glycoprotein that exists as several isoforms (1). The amino acid sequence of APP contains the amyloid domain, which can be released by a two-step proteolytic cleavage (1). The extracell
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19922874?dopt=Abstract
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