Product Name: TPX2 (D2R5C) XP® Rabbit mAb#12245
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:100
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 827022-32-2
Product: Palbociclib (hydrochloride)
Specificity Sensitivity: TPX2 (D2R5C) XP® Rabbit mAb recognizes endogenous levels of total TPX2 protein.
Species Reactivity: Human, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Lys420 of human TPX2 protein.
Background: The Ras family small GTPase Ran is involved in nuclear envelope formation, assembly of the mitotic spindle, and nuclear transport (1,2). TPX2, a target of active Ran (RanGTP), is a microtubule nucleating protein. TPX2 is inactive when bound to nuclear imp
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25144227?dopt=Abstract
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