Product Name: TPX2 Antibody#8559
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA and 50% glycerol. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 1431697-78-7
Product: CAL-130 (Hydrochloride)
Specificity Sensitivity: TPX2 Antibody recognizes endogenous levels of total TPX2 protein.
Species Reactivity: Human, Monkey
Source Purification: Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Lys420 of human TPX2 protein. Antibodies are purified by protein A and peptide affinity chromatography.
Background: The Ras family small GTPase Ran is involved in nuclear envelope formation, assembly of the mitotic spindle, and nuclear transport (1,2). TPX2, a target of active Ran (RanGTP), is a microtubule nucleating protein. TPX2 is inactive when bound to nuclear imp
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25177110?dopt=Abstract
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