Product Name: TIM-3 (D5D5R™) XP® Rabbit mAb#45208
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry: 1:400
Peptide ELISA:
Storage:
CAS NO.: 23554-99-6
Product: HOE 32020
Specificity Sensitivity: TIM-3 (D5D5R™) XP® Rabbit mAb recognizes endogenous levels of total TIM-3 protein.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with recombinant protein specific to the extracellular domain of human TIM-3 protein.
Background: T cell Ig- and mucin-domain-containing molecules (TIMs) are a family of transmembrane proteins expressed by various immune cells. TIM-3 is an inhibitory molecule that is induced following T cell activation (1-3 ). TIM-3 is expressed by exhausted T cells i
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23322301?dopt=Abstract
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