Product Name: TIM-3 (D3M9R) XP® Rabbit mAb (Mouse Specific)#83882
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:100
Immunohistochemistry: 1:200
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 106050-84-4
Product: Hoechst 33342 analog 2
Specificity Sensitivity: TIM-3 (D3M9R) XP® Rabbit mAb (Mouse Specific) recognizes endogenous levels of total TIM-3 protein.
Species Reactivity: Mouse
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro137 of mouse TIM-3 protein.
Background: T cell Ig- and mucin-domain-containing molecules (TIMs) are a family of transmembrane proteins expressed by various immune cells. TIM-3 is an inhibitory molecule that is induced following T cell activation (1-3 ). TIM-3 is expressed by exhausted T cells i
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23723241?dopt=Abstract
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