Product Name: TDP1 (D8D1B) Rabbit mAb#59710
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation:
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 84371-65-3
Product: Mifepristone
Specificity Sensitivity: TDP1 (D8D1B) Rabbit mAb recognizes endogenous levels of total TDP1 protein.
Species Reactivity: Human, Mouse, Rat
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Pro587 of human TDP1 protein.
Background: Topoisomerases are ubiquitous, conserved enzymes that remove DNA supercoils resulting from processes such as chromosome segregation, DNA replication, transcription, and repair (1). Topoisomerase inhibitors such as camptothecin and etoposide trap the enzym
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24916688?dopt=Abstract
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