Product Name: Symplekin (D5Y3T) Rabbit mAb#13071
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:50
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 164656-23-9
Product: Dutasteride
Specificity Sensitivity: Symplekin (D5Y3T) Rabbit mAb recognizes endogenous levels of total symplekin protein.
Species Reactivity: Human, Mouse, Rat, Monkey
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human symplekin protein.
Background: Symplekin is necessary for 3’-end cleavage and polyadenylation of mRNAs, histone 3’-end processing and polyadenylation in the cytoplasm (1-5). It is thought to act as a scaffolding protein that brings together factors involved in mRNA 3’-end processing (1
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/17142834?dopt=Abstract
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