Product Name: Syk (4D10) Mouse mAb#80460
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:200
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 899805-25-5
Product: CC-930
Specificity Sensitivity: Syk (4D10) Mouse mAb recognizes endogenous levels of total Syk protein.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Trp330 of human Syk protein.
Background: Syk is a protein tyrosine kinase that plays an important role in intracellular signal transduction in hematopoietic cells (1-3). Syk interacts with immunoreceptor tyrosine-based activation motifs (ITAMs) located in the cytoplasmic domains of immune recept
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20876612?dopt=Abstract
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