Product Name: Securin (D2B6O) Rabbit mAb#13445
Application: Dilutions
Western Blotting: 1:1000
Immunoprecipitation: 1:200
Immunohistochemistry:
Peptide ELISA:
Storage: Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. Store at –20°C. Do not aliquot the antibody.
CAS NO.: 666179-74-4
Product: Risperidone (hydrochloride)
Specificity Sensitivity: Securin (D2B6O) Rabbit mAb recognizes endogenous levels of total securin protein. Based on western blot of overexpressed proteins, this antibody will also recognize securin 2 (PTTG2) to a lesser extent.
Species Reactivity: Human
Source Purification: Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Val19 of human securin (PTTG1) protein.
Background: Securin is a regulatory protein that contributes to mitotic checkpoint control, p53 activity, DNA repair, and cell migration. The securin protein prevents premature separation of sister chromatids by inhibiting the protease separase, which cleaves the coh
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/8163392?dopt=Abstract
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